Brain screen - A self-referral, screening program for strokes, falls and dementia risk factors

被引:9
作者
Giladi, N
Mordechovich, M
Gruendlinger, L
Shabtai, H
Merims, D
Naor, S
Baltadzhieva, R
Hausdorff, JM
Gur, AY
Bornstein, NM
机构
[1] Tel Aviv Sourasky Med Ctr, Dept Neurol, Movement Disorders Unit, IL-64239 Tel Aviv, Israel
[2] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
[3] Hebrew Univ Jerusalem, Outpatient Psychiat Clin, Kaplan Med Ctr Rehovot, Hadassah Med Sch, Jerusalem, Israel
关键词
risk factor; prevention; stroke; dementia; fall;
D O I
10.1007/s00415-005-0986-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background Falls, strokes and dementia can be predicted and their occurrence can be delayed or even prevented by treatment of risk factors. The value of screening self-referred adults is unknown. Objectives To assess whether a screening program of self-referred adults provides new and valuable medical information on risk factors for falls, stroke and dementia. Method We examined 514 self-referred people (59% women, mean age 68 +/- 8 years (range 44-89) and 14 +/- 3 years of education) in our '' Brain Screen '' program. Participants completed detailed questionnaires and underwent a neurological examination, computerized gait analysis, carotid Duplex, serum lipid and homocysteine levels, a computerized neuropsychological battery (NeuroTrax (R)) and the Mini-Mental State Exam. Information that was detected by '' Brain Screen '' was compared with the self-reported data. Results Unknown vascular risk factors detected by '' Brain Screen '' included: high cholesterol in 44%, homocysteine > 10 mu mol/L in 20%, > 1mm carotid intima-media thickness in 13%, and carotid narrowing (> 30%) in 2.2%. Unknown risk factors for falls were detected in 66% of the subjects who never fell. Of the 205 subjects (44%) who complained of memory decline, 28% had objective memory disturbances compared with their age group. Mild cognitive impairment (amnestic MCI) was clinically diagnosed in 17% of the population and dementia in 5%. Conclusion Screening self-referred adults for falls, strokes and dementia risk factors detected significant unknown risk factors that can be treated in more than one-third of the participants. A national '' Brain Screen '' program can have significant impact on the health of the aging population.
引用
收藏
页码:307 / 315
页数:9
相关论文
共 41 条
[1]   Stroke prevention, blood cholesterol, and statins [J].
Amarenco, P ;
Lavallée, P ;
Touboul, PJ .
LANCET NEUROLOGY, 2004, 3 (05) :271-278
[2]  
[Anonymous], GERIATRIC DEPRESSION
[3]  
[Anonymous], 2003, Acta Neuropsychologica
[4]  
[Anonymous], 2001, J AM GERIATR SOC, V49, P664, DOI DOI 10.1046/J.1532-5415.2001.49115.X
[5]   Dietary intake of folate and risk of stroke in US men and women - NHANES I Epidemiologic Follow-up Study [J].
Bazzano, LA ;
He, J ;
Ogden, LG ;
Loria, C ;
Vupputuri, S ;
Myers, L ;
Whelton, PK .
STROKE, 2002, 33 (05) :1183-1188
[6]   C-reactive protein, carotid intima-media thickness, and incidence of ischemic stroke in the elderly - The Cardiovascular Health Study [J].
Cao, JJ ;
Thach, C ;
Manolio, TA ;
Psaty, BM ;
Kuller, LH ;
Chaves, PHM ;
Polak, JF ;
Sutton-Tyrrell, K ;
Herrington, DM ;
Price, TR ;
Cushman, M .
CIRCULATION, 2003, 108 (02) :166-170
[7]   Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [J].
Chobanian, AV ;
Bakris, GL ;
Black, HR ;
Cushman, WC ;
Green, LA ;
Izzo, JL ;
Jones, DW ;
Materson, BJ ;
Oparil, S ;
Wright, JT ;
Roccella, EJ .
HYPERTENSION, 2003, 42 (06) :1206-1252
[8]   Atherosclerotic vascular disease conference - Writing group V: Medical decision making and therapy [J].
Creager, MA ;
Jones, DW ;
Easton, JD ;
Halperin, JL ;
Hirsch, AT ;
Matsumoto, AH ;
O'Gara, PT ;
Safian, RD ;
Schwartz, GL ;
Spittell, JA .
CIRCULATION, 2004, 109 (21) :2634-2642
[9]  
Doniger Glen M., 2005, Current Alzheimer Research, V2, P117
[10]   Validity of a novel computerized cognitive battery for mild cognitive impairment [J].
Tzvi Dwolatzky ;
Victor Whitehead ;
Glen M Doniger ;
Ely S Simon ;
Avraham Schweiger ;
Dena Jaffe ;
Howard Chertkow .
BMC Geriatrics, 3 (1)