Synthesis and electrochemistry of 5-ferrocene-glucosamide, 5-ferrocene-glucosamide phosphate and 5-ferrocene-amido-5-adenosine in aqueous solution

被引：33

作者：

Chahma, M

Lee, JS

Kraatz, HB

机构：

[1] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada

[2] Univ Saskatchewan, Dept Biochem, Saskatoon, SK S7N 5E5, Canada

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2002年 / 648卷 / 1-2期

基金：

加拿大自然科学与工程研究理事会;

关键词：

bioconjugate ferrocene; electrochemistry; glucosamine; amino sugar; nucleoside;

D O I：

10.1016/S0022-328X(01)01414-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The syntheses of new ferrocene-monosaccharide compounds, 5-ferrocene-glucosamide (4), 5-ferrocene-glucosamido-2'-phosphate (5), and 5'-ferrocene-amido-5'-deoxyadenosine (6), are reported starting from ferrocenoyl hydroxybenzotriazole ester and the corresponding amino sugars. All compounds are investigated spectroscopically. In addition, their redox properties are investigated by cyclic voltarnmetry in aqueous solution. These compounds show a reversible one-electron oxidation. This redox potential in the case of 4 exhibits a significant pH dependence. (C) 2002 Elsevier Science B.V. All rights reserved.

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页码：81 / 86

页数：6

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