Investigations of the reaction mechanisms of 1,2-indanediones with amino acids

被引：33

作者：

Petrovskaia, O ^{[1
]}

Taylor, BM ^{[1
]}

Hauze, DB ^{[1
]}

Carroll, PJ ^{[1
]}

Joullié, MM ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 23期

关键词：

D O I：

10.1021/jo0105179

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction mechanisms of amino acids with a new class of fluorogenic reagents were investigated. The structures of colored and fluorescent species formed in these reactions were partially confirmed by experimental evidence. Reaction intermediates, C-N-C 1,3-dipoles derived from imines, were trapped with dipolarophiles in 3 + 2 cycloadditions to form spiropyrrolidines.

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收藏

页码：7666 / 7675

页数：10

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