Last year provided new structural data, particularly for the group I intron and the Hepatitis delta ribozymes, that were essential for a better understanding of the RNA structure/function relationship. The role of metal ions in catalysis of ribozyme action still remains elusive, however. In vitro selection has continued to be a rich source for obtaining data on new nucleic acid enzyme activities.
机构:
Yale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USAYale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USA
Batey, RT
Doudna, JA
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机构:
Yale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USAYale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USA
机构:
Yale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USAYale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USA
Batey, RT
Doudna, JA
论文数: 0引用数: 0
h-index: 0
机构:
Yale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USAYale Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06511 USA