Secular trends in incidence and antimicrobial resistance among clinical isolates of salmonella at a university hospital in Taiwan, 1983-1999

被引:27
作者
Su, LH
Chiu, CH
Kuo, AJ
Chia, JH
Sun, CF
Leu, HS
Wu, TL
机构
[1] Chang Gung Mem Hosp, Dept Clin Pathol, Lin Kou Med Ctr, Taoyuan 333, Taiwan
[2] Chang Gung Mem Hosp, Dept Internal Med, Div Infect Dis, Taoyuan 333, Taiwan
[3] Chang Gung Childrens Hosp, Dept Paediat, Div Paediat Infect Dis, Taoyuan 333, Taiwan
关键词
D O I
10.1017/S0950268801005957
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The incidence and antimicrobial resistance among clinical isolates of salmonella at a university hospital in Taiwan between 1983 and 1999 are summarized in this report. A total of 7986 isolates were analysed. Serogroup B has been the most prevalent over the years, with an apparently continuous decline after 1995. Concordant decrease was also found among S. choleraesuis and S. typhi isolates in recent years. In contrast, the proportion of serogroup D strains increased significantly after 1996. S. typhi remained relatively susceptible to most of the antimicrobial agents examined. For non-typhoidal isolates, antimicrobial resistance to ampicillin (62%), chloramphenicol (67%), and sulfamethoxazole-trimethoprim (37%) was relatively higher than that reported elsewhere. Newer generation cephalosporins and fluoroquinolones remained effective over the years, although emerging resistance to these drugs has been noticed since 1992. A more prudent selection and use of antimicrobial agents, in both humans and animals, and a continuous surveillance of resistance are essential in the future.
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页码:207 / 213
页数:7
相关论文
共 30 条
[1]   IN-VITRO ACTIVITY OF 8 ANTIBIOTICS AGAINST SALMONELLA AND SHIGELLA SPECIES [J].
ARMAN, D ;
WILLKE, A ;
TURAL, D .
EUROPEAN JOURNAL OF EPIDEMIOLOGY, 1994, 10 (03) :345-347
[2]   EFFECT OF ANTIBIOTIC THERAPY IN ACUTE SALMONELLOSIS ON FECAL EXCRETION OF SALMONELLAE [J].
ASERKOFF, B ;
BENNETT, JV .
NEW ENGLAND JOURNAL OF MEDICINE, 1969, 281 (12) :636-&
[3]   A clinical trial comparing oral azithromycin, cefixime and no antibiotics in the treatment of acute uncomplicated Salmonella enteritis in children [J].
Chiu, CH ;
Lin, TY ;
Ou, JT .
JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 1999, 35 (04) :372-374
[4]   Prevalence of the virulence plasmids of nontyphoid Salmonella in the serovars isolated from humans and their association with bacteremia [J].
Chiu, CH ;
Lin, TY ;
Ou, JI .
MICROBIOLOGY AND IMMUNOLOGY, 1999, 43 (09) :899-903
[5]  
Chiu CH, 1999, INT J CLIN PRACT, V53, P161
[6]  
Chiu Cheng-Hsun, 2000, Acta Paediatrica Taiwanica, V41, P28
[7]   Changes in antimicrobial resistance among Salmonella enterica serovar typhimurium isolates from humans and cattle in the northwestern United States, 1982-1997 [J].
Davis, MA ;
Hancock, DD ;
Besser, TE ;
Rice, DH ;
Gay, JM ;
Gay, C ;
Gearhart, L ;
DiGiacomo, R .
EMERGING INFECTIOUS DISEASES, 1999, 5 (06) :802-806
[8]  
Farmer J. J. Iii, 1995, P438
[9]   Increasing ciprofloxacin resistance in salmonellas in England and Wales 1991-1994 [J].
Frost, JA ;
Kelleher, A ;
Rowe, B .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1996, 37 (01) :85-91
[10]   MULTIDRUG-RESISTANT TYPHOID-FEVER IN CHILDREN - EPIDEMIOLOGY AND THERAPEUTIC APPROACH [J].
GUPTA, A .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1994, 13 (02) :134-140