Positively regulated expression of the Escherichia coli araBAD promoter in Corynebacterium glutamicum

In Corynebacterium glutamicum the promoter of the araBAD Escherichia coli gene is positively regulated by both arabinose and the araC gene product, as it is the case in the natural host. If the L-arabinose inducer and an active araC gene are present, significant amounts of araBAD promoter expression take place in the absence of the E. coli CRP protein. These results show that the C. glutamicum RNA polymerase is activated by the E. coli positive regulator of transcription AraC. (C) 1999 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.