The place of the protease inhibitors in antiretroviral combination therapy

被引：1

作者：

Aboulker, JP

机构：

来源：

CURRENT OPINION IN INFECTIOUS DISEASES | 1996年 / 9卷 / 01期

关键词：

D O I：

10.1097/00001432-199602000-00005

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Combination therapy with nucleoside analogues has recently been demonstrated to be a major advance in the treatment of HIV infected persons. If, as expected, the progress is mostly attributable to a greater inhibition of HIV replication, other combinations might do even better. HIV protease inhibitors form a new and promising class of antiviral agents. Recent findings argue for including protease inhibitors in multiple drug regimens rather than using them individually.

引用

页码：19 / 22

页数：4

共 22 条

[1] HIV POPULATION-DYNAMICS IN-VIVO - IMPLICATIONS FOR GENETIC-VARIATION, PATHOGENESIS, AND THERAPY [J].

COFFIN, JM .

SCIENCE, 1995, 267 (5197) :483-489

[2] IN-VIVO EMERGENCE OF HIV-1 VARIANTS RESISTANT TO MULTIPLE PROTEASE INHIBITORS [J].

CONDRA, JH ;

SCHLEIF, WA ;

BLAHY, OM ;

GABRYELSKI, LJ ;

GRAHAM, DJ ;

QUINTERO, JC ;

RHODES, A ;

ROBBINS, HL ;

ROTH, E ;

SHIVAPRAKASH, M ;

TITUS, D ;

YANG, T ;

TEPPLER, H ;

SQUIRES, KE ;

DEUTSCH, PJ ;

EMINI, EA .

NATURE, 1995, 374 (6522) :569-571

[3]

DANNER SA, 1995, 4 INT WORKSH HIV DRU

[4] COMBINATION AND MONOTHERAPY WITH ZIDOVUDINE AND ZALCITABINE IN PATIENTS WITH ADVANCED HIV DISEASE [J].

FISCHL, MA ;

STANLEY, K ;

COLLIER, AC ;

ARDUINO, JM ;

STEIN, DS ;

FEINBERG, JE ;

ALLAN, JD ;

GOLDSMITH, JC ;

POWDERLY, WG ;

RAINES, CP ;

MAYJO, KJ ;

KERULY, JC ;

CRAVEN, D ;

HIRSHORN, L ;

HIRSCH, MS ;

JAYAWEERA, DT ;

YOUNG, SW ;

PATRONEREESE, J ;

BRETTLER, D ;

SPERBER, K ;

GERITS, P ;

SEREMETIS, S ;

GILL, JC ;

GELB, LD ;

MCGUIRE, ML ;

STIFFLER, T ;

LEDERMAN, MM ;

CAREY, JT ;

WALLACE, M ;

MACARTHUR, RD ;

BERGE, P ;

MILDVAN, D ;

COREY, L ;

COOMBS, RW ;

CUMMINGS, DK ;

SCHOOLEY, RT ;

RAY, MG ;

WAITE, V ;

KURITZKES, DR ;

FUHRER, J ;

TENZLER, RJ ;

DONLON, W ;

VANDERHORST, CM ;

TROIANI, L ;

HORTON, J ;

LANE, TW ;

MURPHY, RR ;

PHAIR, JP ;

KESSLER, HA ;

BENSON, CA .

ANNALS OF INTERNAL MEDICINE, 1995, 122 (01) :24-32

[5]

HAMMER S, 1995, 35 INT C ANT CHEM SA

[6]

HARRIGAN PR, 1994, AIDS S4, V8, P7

[7] RAPID TURNOVER OF PLASMA VIRIONS AND CD4 LYMPHOCYTES IN HIV-1 INFECTION [J].

HO, DD ;

NEUMANN, AU ;

PERELSON, AS ;

CHEN, W ;

LEONARD, JM ;

MARKOWITZ, M .

NATURE, 1995, 373 (6510) :123-126

[8]

JACOBSEN H, 1995, 4 INT WORKSH HIV DRU

[9]

KATLAMA C, 1995, 2 NAT C HUM RETR WAS

[10] SAFETY AND ACTIVITY OF SAQUINAVIR IN HIV-INFECTION [J].

KITCHEN, VS ;

SKINNER, C ;

ARIYOSHI, K ;

LANE, EA ;

DUNCAN, IB ;

BURCKHARDT, J ;

BURGER, HU ;

BRAGMAN, K ;

PINCHING, AJ ;

WEBER, JN .

LANCET, 1995, 345 (8955) :952-955

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