Synthesis, X-ray diffraction and solid-state P-31 magic angle spinning NMR study of alpha-tricalcium orthophosphate

被引:37
作者
Bohner, M [1 ]
Lemaitre, J [1 ]
Legrand, AP [1 ]
delaCaillerie, JBD [1 ]
Belgrand, P [1 ]
机构
[1] ECOLE SUPER PHYS & CHIM IND VILLE PARIS,CNRS URA 1428,PHYS QUANT LAB,F-75231 PARIS 05,FRANCE
关键词
D O I
10.1007/BF00122016
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The effects of synthesis conditions on the quantitative preparation of alpha-tricalcium phosphate (alpha-TCP) have been investigated. The following parameters of the synthesis were considered: nature of the starting material - Ca-deficient hydroxyapatite, DAP, versus hydroxyapatite-anhydrous dicalcium phosphate mixtures (HAP-DCPA); Ca/P atomic ratio of the mixture, calcination temperature and time, and cooling rate. The yield and crystallinity of the final product have been estimated using X-ray diffraction (XRD) and solid state P-31 magic angle spinning NMR (MAS-NMR) techniques. The results show that pure, well-crystallized alpha-TCP powders exhibiting nearly ideal MAS-NMR spectra, can be obtained by reactive sintering of HAP-DCPA (Ca/P = 1.50...1.52) mixtures, at 1400 degrees C for 8 h. The broadening of MAS-NMR spectra can be used as an indicator of structural order in the final product. The alpha-TCP yield with DAP was always less than 50%.
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页码:457 / 463
页数:7
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