Phosphine/Lewis acid mediated reformatsky-type reaction of α-bromoketone or -thioester derivatives

被引：17

作者：

Hashimoto, Y ^{[1
]}

Kikuchi, S ^{[1
]}

机构：

[1] Univ Tokyo, Sch Engn, Dept Chem & Biotechnol, Bunkyo Ku, Tokyo 1138656, Japan

来源：

CHEMISTRY LETTERS | 2002年 / 02期

关键词：

D O I：

10.1246/cl.2002.126

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The combination Of (o-tolyl)(3)P/TiCl4 effectively promoted the Reformatsky-type reaction of alpha-bromoketone or -thioester derivatives with various aldehydes, and the corresponding beta-hydroxy carbonyl compounds were obtained in good yield with high diastereoselectivity.

引用

页码：126 / 127

页数：2

共 9 条

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