Immunoadhesins: Principles and applications

被引：73

作者：

Chamow, SM ^{[1
]}

Ashkenazi, A ^{[1
]}

机构：

[1] GENENTECH INC,DEPT MOLEC ONCOL,S SAN FRANCISCO,CA 94080

来源：

TRENDS IN BIOTECHNOLOGY | 1996年 / 14卷 / 02期

关键词：

D O I：

10.1016/0167-7799(96)80921-8

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The prototypic immunoadhesin is an antibody-like molecule that fuses the Fc region of an immunoglobulin and the ligand-binding region of a receptor or adhesion molecule. In this article, we review some important structural and functional principles of immunoadhesins. In addition, we highlight some unique advantages of immunoadhesins as experimental tools in biology, as well as some of their exciting potential applications in medicine.

引用

页码：52 / 60

页数：9

共 95 条

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