Coexistence of a graft with the preserved native liver in auxiliary partial orthotopic liver transplantation from a living donor for ornithine transcarbamylase deficiency

Background. Auxiliary partial orthotopic liver transplantation (APOLT) has recently been performed in patients with noncirrhotic metabolic liver diseases. However, long-term outcomes for the preserved native Liver and the transplanted liver graft have not been clearly established yet. Methods. The recipient was a 36-month-old girl with ornithine transcarbamylase deficiency. She underwent APOLT, using her father's left lateral segment. Results. Liver function was normalized soon after APOLT and the patient was able to ingest a normal diet without medication Coexistence of the well-functioning native liver and graft was demonstrated in a computed tomography scan, Doppler ultrasonography, scintigraphy, and histological examination, during a relatively long-term follow-up period. Conclusions. APOLT seems to be most useful far the treatment of noncirrhotic metabolic liver diseases.