Health benefits of solar UV-B radiation: Cancer risk reduction

被引:7
作者
Grant, WB [1 ]
机构
[1] NASA, Langley Res Ctr, Hampton, VA 23665 USA
来源
ULTRAVIOLET GROUND- AND SPACE-BASED MEASUREMENTS, MODELS, AND EFFECTS | 2002年 / 4482卷
关键词
D O I
10.1117/12.452935
中图分类号
V [航空、航天];
学科分类号
08 ; 0825 ;
摘要
Based on geographical distributions of various cancers in the U.S. and elsewhere, ecologic studies comparing these distributions to indices of solar radiation during the past 20 years have led to the understanding that solar UV-B radiation is a risk reduction factor for breast, colon, ovarian, prostate cancer and non-Hodgkin's lymphoma (NHL). Photo-initiated production of vitamin D is the mechanism that enables solar UV-B to play this role. The work presented here explores the use of the USDA UVB Radiation Monitoring Program ground station values to confirm and extend the prior results, and compares these results to those obtained using UV-B data from the Total Ozone Mapping Spectrometer (TOMS). Inverse correlations between solar UV-B radiation have been found for a total of 14 cancers using mortality data from the U.S. with these data sets, and are supported by additional studies using cancer mortality and dietary supply data from Europe. While vitamin D has been shown to be a risk reduction factor for several of these cancers, it is hoped that additional studies will be conducted to confirm or disprove the protective role of UV-B and/or vitamin D for the remaining cancers.
引用
收藏
页码:324 / 334
页数:11
相关论文
共 42 条
[1]  
Atillasoy ES, 1998, AM J PATHOL, V152, P1179
[2]  
Bigelow DS, 1998, B AM METEOROL SOC, V79, P601, DOI 10.1175/1520-0477(1998)079<0601:TUURMP>2.0.CO
[3]  
2
[4]   Establishing the stability of multifilter UV rotating shadow-band radiometers [J].
Bigelow, DS ;
Slusser, JR .
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2000, 105 (D4) :4833-4840
[5]  
CHEN TC, 2001, PHOTODERMATOL PHOTO, V17, P140
[6]   Effect of calcium and vitamin D supplementation on bone, density in men and women 65 years of age or older [J].
DawsonHughes, B ;
Harris, SS ;
Krall, EA ;
Dallal, GE .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (10) :670-676
[7]  
DEVESA SS, NIH PUBLICATION
[8]   THE CAUSES OF CANCER - QUANTITATIVE ESTIMATES OF AVOIDABLE RISKS OF CANCER IN THE UNITED-STATES TODAY [J].
DOLL, R ;
PETO, R .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1981, 66 (06) :1191-+
[9]   Editorial/mini-review: Vitamin D and prostate cancer [J].
Feldman, D ;
Zhao, XY ;
Krishnan, AV .
ENDOCRINOLOGY, 2000, 141 (01) :5-9
[10]   Residential and occupational exposure to sunlight and mortality from non-Hodgkin's lymphoma: Composite (threefold) case-control study [J].
Freedman, DM ;
Zahm, SH ;
Dosemeci, M .
BRITISH MEDICAL JOURNAL, 1997, 314 (7092) :1451-1455