HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient

被引：41

作者：

Coppola, Nicola ^{[1
]}

Loquercio, Giovanna ^{[2
]}

Tonziello, Gilda ^{[1
]}

Azzaro, Rosa ^{[2
]}

Pisaturo, Mariantonietta ^{[1
]}

Di Costanzo, Gaetano ^{[2
]}

Starace, Mario ^{[1
]}

Pasquale, Giuseppe ^{[1
]}

Cacciapuoti, Carmela ^{[2
]}

Petruzziello, Arnolfo ^{[2
]}

机构：

[1] Univ Naples 2, Dept Mental Hlth & Publ Med, Infect Dis Sect, I-80133 Naples, Italy

[2] Fdn G Pascale IRCCS Italia, Ist Nazl Tumori, Lab Virol & Mol Biol V Tridente, Transfus Serv,Dept Haematol, Naples, Italy

来源：

JOURNAL OF CLINICAL VIROLOGY | 2013年 / 58卷 / 01期

关键词：

HBV infection; Occult HBV infection; HBsAg mutants; Transfusion; HEPATITIS-B-VIRUS; SURFACE PROTEIN; BLOOD-DONORS; INFECTION; DIAGNOSIS; VARIANTS; STRAINS; IMPACT; ASSAYS;

D O I：

10.1016/j.jcv.2013.06.020

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg. (C) 2013 Published by Elsevier B. V.

引用

页码：315 / 317

页数：3

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