Transient elastography (FibroScan)

被引：224

作者：

de Ledinghen, V. ^{[1
]}

Vergniol, J.

机构：

[1] Hop Haut Leveque, Ctr Invest Fibrose Hepat, F-33604 Pessac, France

来源：

GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE | 2008年 / 32卷

关键词：

Transient; elastography; FibroScan; Liver fibrosis; Cirrhosis;

D O I：

10.1016/S0399-8320(08)73994-0

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Transient elastography (FibroScan) is a non-invasive method proposed for the assessment of hepatic fibrosis in patients with chronic liver disease by measuring liver stiffness. It can be easily performed at the bedside or in the outpatients clinic with immediate results and good reproducibility. Limitations include failure (no value) in around 5% of cases, mainly in patients with substantial thoracic fat. In France, FibroScan or FibroTest are recommended for the initial evaluation of liver fibrosis in previously untreated patients with chronic hepatitis C and no concomitant health disorders. FibroScan is validated for the diagnosis of significant fibrosis and cirrhosis in chronic hepatitis C, recurrence of hepatitis C after liver transplantation, co-infections in HIV-HCV patients and chronic cholestatic diseases, but needs further evaluation in other chronic liver diseases. FibroScan is an excellent tool for early detection of cirrhosis and evaluation of portal hypertension, for which it may have prognostic value as well. Studies are needed using FibroScan for the follow-up of patients with and without treatment, and for the screening of patients at risk of liver disease. However, although FibroScan is a good method for the evaluation of fibrosis in patients with chronic liver disease, it has to be borne in mind that FibroScan evaluates liver stiffness. Therefore, FibroScan values have to be interpreted according to clinical, biological and morphological data. (C) 2008 Elsevier Masson SAS. All rights reserved.

引用

页码：58 / 67

页数：10

共 35 条

[1] Diagnosis of liver fibrosis using FibroScan and other noninvasive methods in patients with hemochromatosis:: A prospective study [J].

Adhoute, X. ;

Foucher, J. ;

Laharie, D. ;

Terrebonne, E. ;

Vergniol, J. ;

Castera, L. ;

Lovato, B. ;

Chanteloup, E. ;

Merrouche, W. ;

Couzigou, P. ;

de Ledinghen, V. .

GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 2008, 32 (02) :180-187

[2] Acute viral hepatitis increases liver stiffness values measured by transient elastography [J].

Arena, Umberto ;

Vizzutti, Francesco ;

Corti, Giampaolo ;

Ambu, Silvia ;

Stasi, Cristina ;

Bresci, Silvia ;

Moscarella, Stefania ;

Boddi, Vied ;

Petrarca, Antonio ;

Laffi, Giacomo ;

Marra, Fabio ;

Pinzani, Massimo .

HEPATOLOGY, 2008, 47 (02) :380-384

[3] Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients:: Fibrotest predicts the presence and Fibroscan® predicts the absence of significant liver fibrosis [J].

Berends, Maartje A. M. ;

Snoek, Josje ;

de Jong, Elke M. G. J. ;

Van Krieken, J. Han ;

de Knegt, Robert J. ;

van Oijen, Martijn G. H. ;

van de Kerkhof, Peter C. M. ;

Drenth, Joost. P. H. .

LIVER INTERNATIONAL, 2007, 27 (05) :639-645

[4] Transient elastography accurately predicts presence of significant portal hypertension in patients with chronic liver disease [J].

Bureau, C. ;

Metivier, S. ;

Peron, J. M. ;

Selves, J. ;

Robic, M. A. ;

Gourraud, P. A. ;

Rouquet, O. ;

Dupuis, E. ;

Alric, L. ;

Vinel, J. P. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2008, 27 (12) :1261-1268

[5] Transient elastography for diagnosis of advanced fibrosis and portal hypertension in patients with hepatitis C recurrence after liver transplantation [J].

Carrion, Jose A. ;

Navasa, Miquel ;

Bosch, Jaume ;

Bruguera, Miquel ;

Gilabert, Rosa ;

Forns, Xavier .

LIVER TRANSPLANTATION, 2006, 12 (12) :1791-1798

[6] Prospective comparison of transient elastography, fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C [J].

Castéra, L ;

Vergniol, J ;

Foucher, J ;

Le Bail, B ;

Chanteloup, E ;

Haaser, M ;

Darriet, M ;

Couzigou, P ;

De Lédinghen, V .

GASTROENTEROLOGY, 2005, 128 (02) :343-350

[7] Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases [J].

Coco, B. ;

Oliveri, F. ;

Maina, A. M. ;

Ciccorossi, P. ;

Sacco, R. ;

Colombatto, P. ;

Bonino, F. ;

Brunetto, M. R. .

JOURNAL OF VIRAL HEPATITIS, 2007, 14 (05) :360-369

[8] Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC [J].

Corpechot, C ;

El Naggar, A ;

Poujol-Robert, A ;

Ziol, M ;

Wendum, D ;

Chazouillères, O ;

De Lédinghen, V ;

Dhumeaux, D ;

Marcellin, P ;

Beaugrand, M ;

Poupon, R .

HEPATOLOGY, 2006, 43 (05) :1118-1124

[9]

de Lédinghen V, 2006, JAIDS-J ACQ IMM DEF, V41, P175

[10] Liver stiffness measurement in children using FibroScan:: Feasibility study and comparison with fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy [J].

de Ledinghen, Victor ;

Le Bail, Brigitte ;

Rebouissoux, Laurent ;

Fournier, Celine ;

Foucher, Juliette ;

Miette, Veronique ;

Castera, Laurent ;

Sandrin, Laurent ;

Merrouche, Wassil ;

Lavrand, Frederic ;

Lamireau, Thierry .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2007, 45 (04) :443-450

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