NF-κB and the regulation of hematopoiesis

被引：107

作者：

Bottero, V ^{[1
]}

Withoff, S ^{[1
]}

Verma, IM ^{[1
]}

机构：

[1] Salk Inst Biol Studies, Genet Lab, La Jolla, CA 92037 USA

来源：

CELL DEATH AND DIFFERENTIATION | 2006年 / 13卷 / 05期

基金：

美国国家卫生研究院;

关键词：

NF-kappa B; I kappa B; IKK; hematopoiesis; myelopoiesis; lymphopoiesis; disease;

D O I：

10.1038/sj.cdd.4401888

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

This review will focus on the role of nuclear factor kappa B (NF-kappa B) signaling in hematopoietic differentiation. We will also discuss several hematopoietic pathologies associated with deregulation of NF-kappa B and their potential therapies.

引用

页码：785 / 797

页数：13

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