Epigenetics as a first exit problem

被引：118

作者：

Aurell, E

Sneppen, K

机构：

[1] SICS, SE-16429 Kista, Sweden

[2] KTH, NADA, SANS, SE-10044 Stockholm, Sweden

[3] NORDITA, DK-2100 Copenhagen, Denmark

来源：

PHYSICAL REVIEW LETTERS | 2002年 / 88卷 / 04期

关键词：

D O I：

10.1103/PhysRevLett.88.048101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We develop a framework to discuss the stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the A prophage. The formalism defines a quantitative measure of robustness of inherited states.

引用

页码：4 / 481014

页数：4

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