The role of MCM/P1 proteins in the licensing of DNA replication

被引：144

作者：

Chong, JPJ

Thommes, P

Blow, JJ

机构：

[1] ICRF Clare Hall Laboratories, Potters Bar, Herts, EN6 3LD, Blanche Lane

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 03期

关键词：

D O I：

10.1016/S0968-0004(96)10013-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The DNA replication licensing system ensures that eukaryotic chromosomes replicate precisely once per cell cycle. A central component of the licensing system, RLF-M, has recently been shown to consist of a complex of Mcm/P1 proteins. This result allows us to integrate data about the MCM/P1 family obtained in different eukaryotes, ranging from yeast to man, into a general picture of the way that chromosome replication is controlled.

引用

页码：102 / 106

页数：5

共 35 条

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