Principles of cargo attachment to cytoplasmic motor proteins

被引：110

作者：

Kamal, A

Goldstein, LSB

机构：

[1] Conforma Therapeut Corp, San Diego, CA 92121 USA

[2] Univ Calif San Diego, Howard Hughes Med Inst, La Jolla, CA 92093 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 01期

关键词：

D O I：

10.1016/S0955-0674(01)00295-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The attachment of cytoskeletal motor proteins to cargo-laden vesicles is crucial for efficient transport in intracellular membrane trafficking pathways. Recent studies have identified specific kinesin-binding and dynein-binding proteins that could serve as membrane-associated 'receptor' proteins for the respective motors. New insights have also emerged about the cargo-binding domains of the motor proteins, and the regulation of motor binding to cargoes.

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页码：63 / 68

页数：6

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