Applications and challenges of DNA microarray technology in military medical research

被引：4

作者：

Draghici, S

Chen, DC

Reffman, J

机构：

[1] Wayne State Univ, Dept Comp Sci, Detroit, MI 48202 USA

[2] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, Bethesda, MD 20814 USA

[3] USA, Med Res & Mat Command, Telemed & Adv Technol Res Ctr, Ft Detrick, MD 21702 USA

来源：

MILITARY MEDICINE | 2004年 / 169卷 / 08期

关键词：

D O I：

10.7205/MILMED.169.8.654

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This review discusses the challenges and applications of DNA microarray technology as it is being used in each of the four major research areas of the U.S. Army Medical Research and Materiel Command: military infectious diseases, combat casualty care, military operational medicine, and medical chemical and biological defense. The overall objective of this review is two-fold. First, the objective is to increase awareness in senior military leadership of the challenges and opportunities presented by DNA microarray technology and the emerging and rapidly changing field of bioinformatics. Second, the aim is to publicize to the civilian research community the additional challenges associated with the use of microarray technology in military medical research. This discussion contains material that would be useful for making programmatic recommendations that team strategic research investments and emerging technologies with U.S. Army Medical Research and Materiel Command resources.

引用

页码：654 / 659

页数：6

共 37 条

[1]

[Anonymous], 2001, REVOLUTION R D GENOM

[2] Applications of gene arrays in environmental toxicology:: Fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene, and trichloroethylene [J].

Bartosiewicz, M ;

Penn, S ;

Buckpitt, A .

ENVIRONMENTAL HEALTH PERSPECTIVES, 2001, 109 (01) :71-74

[3]

BELLAMY RF, 1984, MIL MED, V149, P55

[4]

BOWMAN PD, 2002, ADV TECHNOLOGY APPL

[5]

BOWMAN PD, 2001, APPL CDNA MICROARRAY

[6]

Bugelski PJ, 2002, CURR OPIN DRUG DISC, V5, P79

[7] Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: Report of the pulse trauma work group [J].

Carrico, CJ ;

Holcomb, JB ;

Chaudry, IH .

SHOCK, 2002, 17 (03) :165-168

[8]

CLEGG ED, 2001, CHEM WARF AG TOX C U

[9]

DAS R, 2002, P 23 ARM SCI C DEC 2

[10] Pulmonary gene expression profiling of inhaled ricin [J].

DaSilva, L ;

Cote, D ;

Roy, C ;

Martinez, M ;

Duniho, S ;

Pitt, MLM ;

Downey, T ;

Dertzbaugh, M .

TOXICON, 2003, 41 (07) :813-822

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