Stem cells do play with dice A statistical physics view of transcription

被引:16
作者
Efroni, Sol [2 ]
Melcer, Shai [1 ]
Nissim-Rafinia, Malka [1 ]
Meshorer, Eran [1 ]
机构
[1] Hebrew Univ Jerusalem, Dept Genet, Inst Life Sci, IL-91904 Jerusalem, Israel
[2] Bar Ilan Univ, Fac Life Sci, Ramat Gan, Israel
基金
以色列科学基金会;
关键词
embryonic stem cells; stem cells; transcription; chromatin; microarrays; genome-wide; systems biology; GENE-EXPRESSION; MOLECULAR SIGNATURE; SELF-RENEWAL; MOUSE; CHROMATIN; PLURIPOTENCY; SEQUENCE; OPINION;
D O I
10.4161/cc.8.1.7216
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Embryonic stem cells display wide-spread pervasive transcriptional output. Here, we propose that multiple simultaneous transcriptional states underlay pluripotency.
引用
收藏
页码:43 / 48
页数:6
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