Medical Therapy of Thoracic Aortic Aneurysms

被引：21

作者：

Danyi, Peter ^{[2
]}

Elefteriades, John A. ^{[3
]}

Jovin, Ion S. ^{[1
,3
,4
]}

机构：

[1] McGuire VA Med Ctr, Richmond, VA 23249 USA

[2] Johns Hopkins Univ, Baltimore, MD 21218 USA

[3] Yale Univ, New Haven, CT 06520 USA

[4] Virginia Commonwealth Univ, Richmond, VA 23220 USA

来源：

TRENDS IN CARDIOVASCULAR MEDICINE | 2012年 / 22卷 / 07期

关键词：

BETA-ADRENERGIC-BLOCKADE; CONVERTING ENZYME-INHIBITORS; TYPE-1 RECEPTOR BLOCKER; MARFAN-SYNDROME; GROWTH-RATE; OXIDATIVE STRESS; CONTROLLED-TRIAL; ROOT DILATION; DOUBLE-BLIND; STATIN DRUG;

D O I：

10.1016/j.tcm.2012.07.017

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Thoracic aortic aneurysm is a major health problem with multiple etiologies and potentially devastating consequences. Currently, no large randomized trial has shown that medical therapy can significantly slow or halt the progressive dilatation that eventually leads to dissection and rupture. A recent study that suggested that angiotensin receptor blocking agents slow the development of aneurysm dilatation in Marfan syndrome has revived interest in medical interventions to improve outcomes for patients with aortic aneurysm. In this article, we review the available data on established medical therapies and investigational medical therapies for thoracic aortic aneurysms. (Trends Cardiovasc Med 2012;22:180-184) Published by Elsevier Inc.

引用

收藏

页码：180 / 184

页数：5

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