Irradiated uveal melanomas: Cytopathologic correlation with prognosis

被引：23

作者：

Char, DH

Kroll, SM

Miller, T

Castro, J

Quivey, J

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PATHOL,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT RADIAT ONCOL,SAN FRANCISCO,CA 94143

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 1996年 / 122卷 / 04期

关键词：

D O I：

10.1016/S0002-9394(14)72110-5

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: We analyzed the additional prognostic information from cytopathologic data obtained at the time of uveal melanoma irradiation. METHODS: Fine needle aspiration biopsies (FNABs) were performed and rereviewed in a masked manner. These data and standard prognostic variables were correlated with survival and local tumor recurrence using Kaplan Meier and Cox model statistical techniques. RESULTS: Cytopathologic assessment of cell type added to prognostic accuracy. In 116 patients, the percentage of epithelioid cells on FNAB and ciliary body involvement were most strongly correlated with melanoma-related mortality. CONCLUSIONS: FNAB data improved our prognostic accuracy in irradiated uveal melanoma patients.

引用

页码：509 / 513

页数：5

共 29 条

[1]

AUGSBURGER JJ, 1990, CANCER, V66, P1596, DOI 10.1002/1097-0142(19901001)66:7<1596::AID-CNCR2820660726>3.0.CO

[2]

2-6

[3]

BUTLER P, 1994, OPHTHALMOLOGY, V101, P710

[4]

CHAR DH, 1989, ACTA CYTOL, V33, P599

[5] 5-YEAR FOLLOW-UP OF HELIUM ION THERAPY FOR UVEAL MELANOMA [J].

CHAR, DH ;

CASTRO, JR ;

KROLL, SM ;

IRVINE, AR ;

QUIVEY, JM ;

STONE, RD .

ARCHIVES OF OPHTHALMOLOGY, 1990, 108 (02) :209-214

[6]

CHAR DH, 1993, OPHTHALMOLOGY, V100, P1547

[7] DIAGNOSTIC MODALITIES IN CHOROIDAL MELANOMA [J].

CHAR, DH ;

STONE, RD ;

IRVINE, AR ;

CRAWFORD, JB ;

HILTON, GF ;

LONN, LI ;

SCHWARTZ, A .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 1980, 89 (02) :223-230

[8] ACCURACY OF PRESUMED UVEAL MELANOMA DIAGNOSIS BEFORE ALTERNATIVE THERAPY [J].

CHAR, DH ;

MILLER, T .

BRITISH JOURNAL OF OPHTHALMOLOGY, 1995, 79 (07) :692-696

[9]

CHAR DH, 1991, ANAL QUANT CYTOL, V13, P293

[10]

CHAR DH, 1985, AM J OPHTHALMOL, V98, P796

← 1 2 3 →