A multivariate test of association

被引：188

作者：

Ferreira, Manuel A. R. ^{[1
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Purcell, Shaun M. ^{[1
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机构：

[1] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Dept Psychiat, Cambridge, MA 02138 USA

[3] Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA

[4] Broad Inst Harvard, Stanley Ctr Psychiat Res, Cambridge, MA USA

[5] MIT, Cambridge, MA 02139 USA

[6] Queensland Inst Med Res, Brisbane, Qld 4006, Australia

[7] Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Boston, MA 02114 USA

来源：

BIOINFORMATICS | 2009年 / 25卷 / 01期

基金：

英国医学研究理事会;

关键词：

QUANTITATIVE TRAITS; LINKAGE ANALYSES; POWER;

D O I：

10.1093/bioinformatics/btn563

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Although genetic association studies often test multiple, related phenotypes, few formal multivariate tests of association are available. We describe a test of association that can be efficiently applied to large population-based designs.

引用

页码：132 / 133

页数：2

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