Absorption of topically administered ciprofloxacin, ofloxacin and gentamicin in the inflamed rabbit eye

被引:15
作者
BehrensBaumann, W
机构
[1] Universitäts-Augenklinik der Otto-von-Guericke-Universität Magdeburg, Magdeburg, Medizinische Fakultät
关键词
ciprofloxacin; ofloxacin; gentamicin; animal model; absorption in the inflamed cornea;
D O I
10.1159/000310687
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
The authors evaluated the ocular absorption of ciprofloxacin, ofloxacin and gentamicin as a reference drug in a novel model of ocular inflammation. The ocular absorption of ciprofloxacin and ofloxacin was shown to be increased two- to threefold in the inflamed eye. The absorption of gentamicin was undetectable in the normal eye and very poor in the inflamed eye.
引用
收藏
页码:119 / 122
页数:4
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