Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells

被引：18

作者：

Arranz, Lorena ^{[1
]}

Urbano-Ispizua, Alvaro ^{[2
,3
]}

Mendez-Ferrer, Simon ^{[1
,4
]}

机构：

[1] Natl Ctr Cardiovasc Res CNIC, Stem Cell Niche Pathophysiol Grp, Madrid, Spain

[2] Univ Barcelona, Hosp Clin, Dept Hematol, IDIBAPS, Barcelona, Spain

[3] Inst Res Josep Carreras, Barcelona, Spain

[4] Icahn Sch Med Mt Sinai, Dept Med, New York, NY USA

来源：

HAEMATOLOGICA | 2013年 / 98卷 / 07期

关键词：

BONE-MARROW MICROENVIRONMENT; MULTILINEAGE ENGRAFTMENT; OXIDATIVE STRESS; HYPOXIC NICHE; QUIESCENCE; RECOVERY; TRANSPLANTATION; BIOGENESIS; VARIANTS; LEUKEMIA;

D O I：

10.3324/haematol.2013.084293

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：993 / 995

页数：3

共 30 条

[1]

Peroxisome Proliferator-Activated-γ Coactivator-1α-Mediated Mitochondrial Biogenesis Is Important for Hematopoietic Recovery in Response to Stress [J].

Basu, Sunanda ;

Broxmeyer, Hal E. ;

Hangoc, Giao .

STEM CELLS AND DEVELOPMENT, 2013, 22 (11) :1678-1692

[2]

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species [J].

Chen, Chong ;

Liu, Yu ;

Liu, Runhua ;

Ikenoue, Tsuneo ;

Guan, Kun-Liang ;

Liu, Yang ;

Zheng, Pan .

JOURNAL OF EXPERIMENTAL MEDICINE, 2008, 205 (10) :2397-2408

[3]

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans [J].

De Benedictis, G ;

Rose, G ;

Carrieri, G ;

De Luca, M ;

Falcone, E ;

Passarino, G ;

Bonafé, M ;

Monti, D ;

Baggio, G ;

Bertolini, S ;

Mari, D ;

Mattace, R ;

Franceschi, C .

FASEB JOURNAL, 1999, 13 (12) :1532-1536

[4]

Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation [J].

Forristal, Catherine E. ;

Winkler, Ingrid G. ;

Nowlan, Bianca ;

Barbier, Valerie ;

Walkinshaw, Gail ;

Levesque, Jean-Pierre .

BLOOD, 2013, 121 (05) :759-769

[5]

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment [J].

Frolova, Olga ;

Samudio, Ismael ;

Benito, Juliana ;

Jacamo, Rodrigo ;

Kornblau, Steven M. ;

Markovic, Ana ;

Schober, Wendy ;

Lu, Hongbo ;

Qiu, Yi Hua ;

Buglio, Daniela ;

McQueen, Teresa ;

Pierce, Sherry ;

Shpall, Elizabeth ;

Konoplev, Sergej ;

Thomas, Deborah ;

Kantarjian, Hagop ;

Lock, Richard ;

Andreeff, Michael ;

Konopleva, Marina .

CANCER BIOLOGY & THERAPY, 2012, 13 (10) :858-870

[6]

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells [J].

Gan, Boyi ;

Hu, Jian ;

Jiang, Shan ;

Liu, Yingchun ;

Sahin, Erguen ;

Zhuang, Li ;

Fletcher-Sananikone, Eliot ;

Colla, Simona ;

Wang, Y. Alan ;

Chin, Lynda ;

DePinho, Ronald A. .

NATURE, 2010, 468 (7324) :701-U125

[7]

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival [J].

Gurumurthy, Sushma ;

Xie, Stephanie Z. ;

Alagesan, Brinda ;

Kim, Judith ;

Yusuf, Rushdia Z. ;

Saez, Borja ;

Tzatsos, Alexandros ;

Ozsolak, Fatih ;

Milos, Patrice ;

Ferrari, Francesco ;

Park, Peter J. ;

Shirihai, Orian S. ;

Scadden, David T. ;

Bardeesy, Nabeel .

NATURE, 2010, 468 (7324) :659-U75

[8]

Isern J, 2013, CELL REP

[9]

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells [J].

Ito, K ;

Hirao, A ;

Arai, F ;

Takubo, K ;

Matsuoka, S ;

Miyamoto, K ;

Ohmura, M ;

Naka, K ;

Hosokawa, K ;

Ikeda, Y ;

Suda, T .

NATURE MEDICINE, 2006, 12 (04) :446-451

[10]

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells [J].

Ito, K ;

Hirao, A ;

Arai, F ;

Matsuoka, S ;

Takubo, K ;

Hamaguchi, I ;

Nomiyama, K ;

Hosokawa, K ;

Sakurada, K ;

Nakagata, N ;

Ikeda, Y ;

Mak, TW ;

Suda, T .

NATURE, 2004, 431 (7011) :997-1002

← 1 2 3 →