Keratinocytes in epidermal immune responses

被引：24

作者：

Steinhoff, Martin ^{[1
,2
]}

Brzoska, Thomas ^{[1
,2
]}

Luger, Thomas A. ^{[1
,2
]}

机构：

[1] Univ Munster, Dept Dermatol, Von Esmarch Str 58, D-48129 Munster, Germany

[2] Univ Munster, Boltzmann Inst Cell & Immunobiol Skin, D-48129 Munster, Germany

来源：

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2001年 / 1卷 / 05期

关键词：

D O I：

10.1097/01.all.0000011062.60720.e3

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Recent studies have advanced our understanding that the regulation of immune responses is not only confined to immunocompetent cells. Upon stimulation, keratinocytes are capable of releasing various factors and expressing receptors that are significantly involved in immunoregulation. Dysregulation and the abnormal production of cytokines and other inflammatory mediators as well as their receptors can be observed in various skin diseases. An understanding of keratinocytes as important regulators of the skin immune system opens new opportunities for the treatment of various skin diseases. (C) 2001 Lippincott Williams & Wilkins.

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收藏

页码：469 / 476

页数：8

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