Lung function in relation to intake of carotenoids and other antioxidant vitamins in a population-based study

被引:93
作者
Schünemann, HJ
McCann, S
Grant, BJB
Trevisan, M
Muti, P
Freudenheim, JL
机构
[1] SUNY Buffalo, Sch Med & Biomed Sci, Dept Med, Buffalo, NY 14214 USA
[2] SUNY Buffalo, Sch Med & Biomed Sci, Dept Prevent & Social Med, Buffalo, NY 14214 USA
[3] Vet Adm Med Ctr, Sect Pulm Crit Care & Sleep Med, Buffalo, NY 14215 USA
关键词
airway obstruction; antioxidants; carotenoids; lung diseases; obstructive; oxidants; oxidative stress; respiratory function tests; vitamins;
D O I
10.1093/aje/155.5.463
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Accumulating evidence suggests that dietary antioxidant vitamins are positively associated with lung function. No evidence exists regarding whether dietary carotenoids other than beta-carotene are related to pulmonary function. In 1995-1998 the authors studied the association of forced expiratory volume in 1 second and forced vital capacity as the percentage of the predicted value (FEV1% and FVC%, respectively) after adjustment for height, age, gender, and race with the intakes of several carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein/zeaxanthin, and lycopene) in a random sample of 1,616 men and women who were residents of western New York State, aged 35-79 years, and free from respiratory disease. They observed significant associations of lutein/zeaxanthin and vitamins C and E with FEV1% and FVC% using multiple linear regression after adjustment for total energy intake, smoking, and other covariates. When they analyzed all of these antioxidant vitamins simultaneously, they observed the strongest association of vitamin E with FEV1% and of lutein/zeaxanthin with FVC%. The differences in forced expiratory volume in 1 second and forced vital capacity associated with a decrease of 1 standard deviation of dietary vitamin E or lutein/zeaxanthin were equivalent to the influence of approximately 1-2 years of aging. Their findings support the hypothesis that carotenoids, vitamin C, and vitamin E may play a role in respiratory health and that carotenoids other than beta-carotene may be involved.
引用
收藏
页码:463 / 471
页数:9
相关论文
共 36 条
[2]   A DATA-BASED APPROACH TO DIET QUESTIONNAIRE DESIGN AND TESTING [J].
BLOCK, G ;
HARTMAN, AM ;
DRESSER, CM ;
CARROLL, MD ;
GANNON, J ;
GARDNER, L .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1986, 124 (03) :453-469
[3]  
BLOCK G, 1993, HHHQ DIETSYS ANAL SO
[4]   Structure and properties of carotenoids in relation to function [J].
Britton, G .
FASEB JOURNAL, 1995, 9 (15) :1551-1558
[5]   DIETARY ANTIOXIDANT VITAMIN INTAKE AND LUNG-FUNCTION IN THE GENERAL-POPULATION [J].
BRITTON, JR ;
PAVORD, ID ;
RICHARDS, KA ;
KNOX, AJ ;
WISNIEWSKI, AF ;
LEWIS, SA ;
TATTERSFIELD, AE ;
WEISS, ST .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995, 151 (05) :1383-1387
[6]   Association of dietary antioxidants and waist circumference with pulmonary function and airway obstruction [J].
Chen, RL ;
Tunstall-Pedoe, H ;
Bolton-Smith, C ;
Hannah, MK ;
Morrison, C .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2001, 153 (02) :157-163
[7]  
CROSS CE, 1997, OXYGEN GENE EXPRESSI, P367
[8]   Does dietary intake of vitamins C and E influence lung function in older people? [J].
Dow, L ;
Tracey, M ;
Villar, A ;
Coggon, D ;
Margetts, BM ;
Campbell, MJ ;
Holgate, ST .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1996, 154 (05) :1401-1404
[9]   Serum vitamins, carotenoids, and angina pectoris: Findings from the National Health and Nutrition Examination Survey III [J].
Ford, ES ;
Giles, WH .
ANNALS OF EPIDEMIOLOGY, 2000, 10 (02) :106-116
[10]   BLOOD EOSINOPHILIA AND FEV1 - CROSS-SECTIONAL AND LONGITUDINAL ANALYSES [J].
FRETTE, C ;
ANNESI, I ;
KOROBAEFF, M ;
NEUKIRCH, F ;
DORE, MF ;
KAUFFMANN, F .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 143 (05) :987-992