OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients

被引:20
作者
Zach, Otto [1 ]
Krieger, Otto [1 ]
Foedermayr, Mathilde [1 ]
Zellhofer, Barbara [1 ]
Lutz, Dieter [1 ]
机构
[1] Elisabeth Hosp, Dept Internal Med 1, A-4010 Linz, Austria
关键词
D O I
10.1080/10428190802322893
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:2222 / 2223
页数:2
相关论文
共 4 条
[1]   Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia -: A Europe Against Cancer Program [J].
Gabert, J ;
Beillard, E ;
van der Velden, VHJ ;
Bi, W ;
Grimwade, D ;
Pallisgaard, N ;
Barbany, G ;
Cazzaniga, G ;
Cayuela, JM ;
Cavé, H ;
Pane, F ;
Aerts, JLE ;
De Micheli, D ;
Thirion, X ;
Pradel, V ;
González, M ;
Viehmann, S ;
Malec, M ;
Saglio, G ;
van Dongen, JJM .
LEUKEMIA, 2003, 17 (12) :2318-2357
[2]   How I treat chronic myeloid leukemia in the imatinib era [J].
Goldman, John M. .
BLOOD, 2007, 110 (08) :2828-2837
[3]   Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1 [J].
Shu, Y ;
Leabman, MK ;
Feng, B ;
Mangravite, LM ;
Huang, CC ;
Stryke, D ;
Kawamoto, M ;
Johns, SJ ;
DeYoung, J ;
Carlson, E ;
Ferrin, TE ;
Herskowitz, I ;
Giacomini, KM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (10) :5902-5907
[4]   Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity [J].
White, Deborah L. ;
Saunders, Verity A. ;
Dang, Phuong ;
Engler, Jane ;
Venables, Amity ;
Zrim, Stephanie ;
Zannettino, Andrew ;
Lynch, Kevin ;
Manley, Paul W. ;
Hughes, Timothy .
BLOOD, 2007, 110 (12) :4064-4072