Airway patterning: A paradigm for restricted signalling

被引:16
作者
Placzek, M [1 ]
Skaer, H [1 ]
机构
[1] Univ Sheffield, Krebs Inst, Dev Genet Programme, Sheffield S10 2TN, S Yorkshire, England
基金
英国惠康基金;
关键词
D O I
10.1016/S0960-9822(99)80322-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Intercellular signalling is limited by the range of cell responsiveness, often mediated by repressors. A recently identified repressor, Sprouty, inhibits MAP kinase-signalling in flies, mice and humans and has a conserved function in patterning the airways of these divergent species.
引用
收藏
页码:R506 / R510
页数:5
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