Postoperative management of subthalamic nucleus stimulation for Parkinson's disease

被引:191
作者
Krack, P
Fraix, V
Mendes, A
Benabid, AL
Pollak, P
机构
[1] CHU Grenoble, Serv Neurol, Dept Clin & Biol Neurosci, F-38043 Grenoble, France
[2] Univ Grenoble 1, INSERM Unit 318, Grenoble, France
[3] CHU Grenoble, Serv Neurochirurg, Dept Clin & Biol Neurosci, F-38043 Grenoble, France
关键词
subthalamic nucleus; deep brain stimulation; Parkinson's disease;
D O I
10.1002/mds.10163
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The postoperative neurologic management of patients with deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson' s disease is a complex dynamic process that involves a progressive increase in stimulation intensity and a parallel decrease in antiparkinsonian medication while assessing the interactions of both treatments. Neurologists responsible for postoperative management of patients receiving STN DBS must have expert knowledge of the electroanatomy of the subthalamic area and be familiar with the medical treatment of motor and nonmotor symptoms, including the management of long-term complications of levodopa treatment. Neurosurgeons who perform DBS need to understand the principles that guide the postoperative adaptation of treatment. This article defines guidelines for setting stimulation parameters, adapting drugs and managing adverse effects. (C) 2002 Movement Disorder Society.
引用
收藏
页码:S188 / S197
页数:10
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