SWRred not shaken:: Mixing the histones

被引：52

作者：

Korber, P ^{[1
]}

Hörz, W ^{[1
]}

机构：

[1] Univ Munich, Adolf Butenandt Inst Mol Biol, D-80336 Munich, Germany

来源：

CELL | 2004年 / 117卷 / 01期

关键词：

D O I：

10.1016/S0092-8674(04)00296-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recently isolated SWR1 complex catalyzes an ATP-dependent histone exchange with specificity for the histone variant H2A.Z. This provides a new theme in chromatin remodeling mechanisms and an explanation of how histone variants are incorporated into the nucleosome outside of S phase. In connection with the isolation of histone variant specific chaperone complexes, we are beginning to see the mechanisms that mix the histone octamer with intriguing implications for epigenetic inheritance.

引用

页码：5 / 7

页数：3

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