Role of ASA in the primary and secondary prevention of cardiovascular events

被引：21

作者：

Casado-Arroyo, Ruben ^{[1
]}

Bayrak, Fatih ^{[1
]}

Sarkozy, Andrea ^{[1
]}

Chierchia, Gian-Battista ^{[1
]}

de Asmundis, Carlo ^{[1
]}

Brugada, Pedro ^{[1
]}

机构：

[1] Free Univ Brussels UZ Brussel VUB, Ctr Cardiovasc, Heart Rhythm Management Ctr, B-1090 Brussels, Belgium

来源：

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY | 2012年 / 26卷 / 02期

关键词：

Aspirin; Primary prevention; Secondary prevention; Cardiovascular disease; LOW-DOSE ASPIRIN; PERCUTANEOUS CORONARY INTERVENTION; EXPERT CONSENSUS DOCUMENT; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; ACUTE MYOCARDIAL-INFARCTION; AMERICAN-HEART-ASSOCIATION; TRANSIENT ISCHEMIC ATTACK; FOUNDATION TASK-FORCE; ANTIPLATELET THERAPY; UNSTABLE ANGINA;

D O I：

10.1016/j.bpg.2012.01.013

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Cardiovascular disease, which includes coronary heart disease, cerebrovascular disease and peripheral artery disease, is the leading cause of death in developed countries. Evidence from basic research, clinical investigations, observational epidemiologic studies and randomized clinical trials has provided strong support for the benefits of aspirin in decreasing the risk of cardiovascular events in a wide range of pathologies in secondary prevention. Data in primary prevention have far more uncertainties. An overview for the evidence supporting the efficacy of aspirin in primary and secondary prevention of cardiovascular disease is discussed, including the relative and absolute benefit and the risks of side effects. Finally, future developments in the field directed towards individualized treatment strategies and novel antiplatelet agents are examined. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：113 / 123

页数：11

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