Feeding neural networks in the mollusc Aplysia

被引:85
作者
Cropper, EC [1 ]
Evans, CG [1 ]
Hurwitz, I [1 ]
Jing, J [1 ]
Proekt, A [1 ]
Romero, A [1 ]
Rosen, SC [1 ]
机构
[1] Mt Sinai Sch Med, Dept Physiol & Biophys, New York, NY 10029 USA
关键词
central pattern generator; invertebrate; command-like neurons; feeding;
D O I
10.1159/000076159
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aplysia feeding is striking in that it is executed with a great deal of plasticity. At least in part, this flexibility is a result of the organization of the feeding neural network. To illustrate this, we primarily discuss motor programs triggered via stimulation of the command-like cerebral-buccal interneuron 2 (CBI-2). CBI-2 is interesting in that it can generate motor programs that serve opposing functions, i.e., programs can be ingestive or egestive. When programs are egestive, radula-closing motor neurons are activated during the protraction phase of the motor program. When programs are ingestive, radula-closing motor neurons are activated during retraction. When motor programs change in nature, activity in the radula-closing circuitry is altered. Thus, CBI-2 stimulation stereotypically activates the protraction and retraction circuitry, with protraction being generated first, and retraction immediately thereafter. In contrast, radula-closing motor neurons can be activated during either protraction or retraction. Which will occur is determined by whether other cerebral and buccal neurons are recruited, e. g. radula-closing motor neurons tend to be activated during retraction if a second CBI, CBI-3, is recruited. Fundamentally different motor programs are, therefore, generated because CBI-2 activates some interneurons in a stereotypic manner and other interneurons in a variable manner. Copyright (C) 2004 S. Karger AG, Basel.
引用
收藏
页码:70 / 86
页数:17
相关论文
共 110 条
[1]  
[Anonymous], SEROTONIN NEUROTRANS
[2]   MOTOR CONTROL OF THE APPETITIVE PHASE OF FEEDING-BEHAVIOR IN APLYSIA [J].
BABLANIAN, GM ;
WEISS, KR ;
KUPFERMANN, I .
BEHAVIORAL AND NEURAL BIOLOGY, 1987, 48 (03) :394-407
[3]  
Baxter D. A., 1997, Society for Neuroscience Abstracts, V23, P1044
[4]   Pheromones linked to sexual behaviors excite the appetitive phase of feeding behavior of Aplysia fasciata.: I.: Modulation and excitation of appetitive behaviors [J].
Blumberg, S ;
Haran, T ;
Botzer, D ;
Susswein, AJ ;
Teyke, T .
JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 1998, 182 (06) :777-783
[5]  
Borovikov D, 2000, J NEUROSCI, V20, P1990
[6]   Operant reward learning in Aplysia:: Neuronal correlates and mechanisms [J].
Brembs, B ;
Lorenzetti, FD ;
Reyes, FD ;
Baxter, DA ;
Byrne, JH .
SCIENCE, 2002, 296 (5573) :1706-1709
[7]   MULTIPLE ROLES OF A HISTAMINERGIC AFFERENT NEURON IN THE FEEDING-BEHAVIOR OF APLYSIA [J].
CHIEL, HJ ;
WEISS, KR ;
KUPFERMANN, I .
TRENDS IN NEUROSCIENCES, 1990, 13 (06) :223-227
[8]  
CHIEL HJ, 1986, J NEUROSCI, V6, P2427
[9]  
CHIEL HJ, 1988, J NEUROSCI, V8, P49
[10]   ACTIVITY OF MULTIPLE IDENTIFIED MOTOR-NEURONS RECORDED INTRACELLULARLY DURING EVOKED FEEDINGLIKE MOTOR PROGRAMS IN APLYSIA [J].
CHURCH, PJ ;
LLOYD, PE .
JOURNAL OF NEUROPHYSIOLOGY, 1994, 72 (04) :1794-1809