Beacon-like immunoreactivity in the hypothalamus of Sprague-Dawley rats

被引：14

作者：

Brailoiu, GC

Dun, SL

Yang, J

Chang, JK

Castellino, S

Dun, NJ

机构：

[1] E Tennessee State Univ, James H Quillen Coll Med, Dept Pharmacol, Johnson City, TN 37614 USA

[2] Phoenix Pharmaceut Inc, Belmont, CA 94002 USA

来源：

NEUROSCIENCE LETTERS | 2002年 / 317卷 / 03期

关键词：

feeding behavior; median eminence; paraventricular nucleus; supraoptic nucleus; Psammomys obesus; sand rat;

D O I：

10.1016/S0304-3940(01)02459-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Distribution of the novel peptide beacon in the hypothalamus of Sprague-Dawley rats was examined by immunohistochemical methods. Beacon-immunoreactive (irBC) neurons were found in the paraventricular, supraoptic, and accessory neurosecretory nuclei, and intensely labeled fibers in the median eminence and infundibulo-pituitary stalk. Scattered cells and/or fibers were noted in the suprachiasmatic nucleus, arcuate nucleus, retrochiasmatic area, lateral and medial preoptic area, as well as anterior and lateral hypothalamic area. The wide distribution of irBC in the hypothalamus of Sprague-Dawley rats suggests that the pepticle may influence, in addition to a proposed role in feeding, a multitude of biological activities associated with the hypothalamic-pituitary axis. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

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收藏

页码：166 / 168

页数：3

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