Incidence, Age of Acquisition and Risk Factors of Helicobacter pylori Infection among Israeli Arab Infants

被引：47

作者：

Muhsen, Khitam ^{[1
]}

Jurban, Manal ^{[1
]}

Goren, Sophy ^{[1
]}

Cohen, Dani ^{[1
]}

机构：

[1] Tel Aviv Univ, Sackler Fac Med, Sch Publ Hlth, Dept Epidemiol & Prevent Med, IL-69978 Tel Aviv, Israel

来源：

JOURNAL OF TROPICAL PEDIATRICS | 2012年 / 58卷 / 03期

关键词：

Helicobacter pylori; acquisition; infants; prospective cohort; stool; risk factors; NORTHEASTERN BRAZIL; CHILDREN; PREVALENCE; HISTORY; CHILDHOOD; COLONIZATION; PRESCHOOL; SIBLINGS;

D O I：

10.1093/tropej/fmr068

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We examined the age of acquisition of Helicobacter pylori infection in a prospective study that was conducted among 231 Israeli Arab children. Helicobacter pylori was identified in stool specimens collected at ages 2, 4, 6, 8, 12 and 18 months, using a monoclonal stool antigen immunoassay. Information on household characteristics, breastfeeding, antibiotic use and hygiene practices was obtained. The incidence of H. pylori infection was 33.3%. The estimated mean age of H. pylori infection acquisition was 14 months. The determinants of H. pylori infection were living in a low socioeconomic status (SES) village: OR 9.60 (95% CI 2.91-31.68, p < 0.001); low paternal education: OR 3.35 (95% CI 1.21-9.29, p = 0.02); and boiling feeding bottles and nipples at low frequency: OR 7.12 (95% CI 1.82-27.86, p = 0.005). In conclusion, H. pylori infection is acquired at a higher rate in low SES settings. Parental education and hygiene play an important role in H. pylori acquisition in infancy.

引用

页码：208 / 213

页数：6

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