Shuttle box learning in zebrafish (Danio rerio)

被引:100
作者
Pather, Shalini [1 ]
Gerlai, Robert [1 ]
机构
[1] Univ Toronto, Dept Psychol, Mississauga, ON L5L 1C6, Canada
基金
加拿大自然科学与工程研究理事会; 芬兰科学院;
关键词
Associative learning; Shuttle box; Social behavior; Temporal learning; Zebrafish; MEMORY CONSOLIDATION; BEHAVIOR; QUANTIFICATION; VERTEBRATE; PREFERENCE; SYSTEM; DRUGS;
D O I
10.1016/j.bbr.2008.09.013
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Zebrafish is used in forward genetic and drug screening and is gaining popularity in behavioral brain research but high throughput learning paradigms are lacking. The sight of conspecifics has been shown to be rewarding in zebrafish. Here, in a novel paradigm, subjects learn to respond to alternating presentation of computer-animated zebrafish images. The simplicity and computerization of the paradigm will make it useful for high throughput screening. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:323 / 327
页数:5
相关论文
共 24 条
[1]   Sight of conspecifics as reward in associative learning in zebrafish (Danio rerio) [J].
Al-Imari, Lina ;
Gerlai, Robert .
BEHAVIOURAL BRAIN RESEARCH, 2008, 189 (01) :216-219
[2]   Mutagenesis strategies in zebrafish for identifying genes involved in development and disease [J].
Amsterdam, Adam ;
Hopkins, Nancy .
TRENDS IN GENETICS, 2006, 22 (09) :473-478
[3]   Behavioral phenotyping in zebrafish: Comparison of three behavioral quantification methods [J].
Blaser, Rachel ;
Gerlai, Robert .
BEHAVIOR RESEARCH METHODS, 2006, 38 (03) :456-469
[4]   Visual discrimination learning in zebrafish (Danio rerio) [J].
Colwill, RM ;
Raymond, MP ;
Ferreira, L ;
Escudero, H .
BEHAVIOURAL PROCESSES, 2005, 70 (01) :19-31
[5]   Behavioral screening for cocaine sensitivity in mutagenized zebrafish [J].
Darland, T ;
Dowling, JE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (20) :11691-11696
[6]   Zebrafish in the Wild: A Review of Natural History and New Notes from the Field [J].
Engeszer, Raymond E. ;
Patterson, Larissa B. ;
Rao, Andrew A. ;
Parichy, David M. .
ZEBRAFISH, 2007, 4 (01) :21-U126
[7]   Learned social preference in zebrafish [J].
Engeszer, RE ;
Ryan, MJ ;
Parichy, DM .
CURRENT BIOLOGY, 2004, 14 (10) :881-884
[8]   Timeline - Headwaters of the zebrafish emergence of a new model vertebrate [J].
Grunwald, DJ ;
Eisen, JS .
NATURE REVIEWS GENETICS, 2002, 3 (09) :717-724
[9]   Automated analysis of behavior: A computer-controlled system for drug screening and the investigation of learning [J].
Hicks, Caitlin ;
Sorocco, Debra ;
Levin, Michael .
JOURNAL OF NEUROBIOLOGY, 2006, 66 (09) :977-990
[10]   Dissociation of food and opiate preference by a genetic mutation in zebrafish [J].
Lau, B. ;
Bretaud, S. ;
Huang, Y. ;
Lin, E. ;
Guo, S. .
GENES BRAIN AND BEHAVIOR, 2006, 5 (07) :497-505