Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity

被引:120
作者
Bendelac, A
Medzhitov, R
机构
[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
[2] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USA
[3] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA
关键词
D O I
10.1084/jem.20020073
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:F19 / F23
页数:5
相关论文
共 43 条
  • [1] Toll-like receptors: critical proteins linking innate and acquired immunity
    Akira, S
    Takeda, K
    Kaisho, T
    [J]. NATURE IMMUNOLOGY, 2001, 2 (08) : 675 - 680
  • [2] Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway
    Basu, S
    Binder, RJ
    Suto, R
    Anderson, KM
    Srivastava, PK
    [J]. INTERNATIONAL IMMUNOLOGY, 2000, 12 (11) : 1539 - 1546
  • [3] Autoreactivity by design: Innate B and T lymphocytes
    Bendelac, A
    Bonneville, M
    Kearney, JF
    [J]. NATURE REVIEWS IMMUNOLOGY, 2001, 1 (03) : 177 - 186
  • [4] Help for cytotoxic-T-cell responses is mediated by CD40 signalling
    Bennett, SRM
    Carbone, FR
    Karamalis, F
    Flavell, RA
    Miller, JFAP
    Heath, WR
    [J]. NATURE, 1998, 393 (6684) : 478 - 480
  • [5] Carnaud C, 1999, J IMMUNOL, V163, P4647
  • [6] Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Vα14 natural killer T cells
    Cui, JQ
    Watanabe, N
    Kawano, T
    Yamashita, M
    Kamata, T
    Shimizu, C
    Kimura, M
    Shimizu, E
    Koike, J
    Koseki, H
    Tanaka, Y
    Taniguchi, M
    Nakayama, T
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (06) : 783 - 792
  • [7] C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
    Dempsey, PW
    Allison, MED
    Akkaraju, S
    Goodnow, CC
    Fearon, DT
    [J]. SCIENCE, 1996, 271 (5247) : 348 - 350
  • [8] Eberl G, 2000, EUR J IMMUNOL, V30, P985, DOI 10.1002/(SICI)1521-4141(200004)30:4<985::AID-IMMU985>3.0.CO
  • [9] 2-E
  • [10] Elements of immunity - The instructive role of innate immunity in the acquired immune response
    Fearon, DT
    Locksley, RM
    [J]. SCIENCE, 1996, 272 (5258) : 50 - 54