The synthesis of isochroman-4-ols and isochroman-3-ols:: models for naturally occurring benzo[g]isochromanols

被引：24

作者：

de Koning, CB ^{[1
]}

Green, IR

Michael, JP

Oliveira, JR

机构：

[1] Univ Witwatersrand, Inst Mol Sci, Sch Chem, ZA-2050 Wits, South Africa

[2] Univ Western Cape, Dept Chem, ZA-7535 Bellville, South Africa

来源：

TETRAHEDRON | 2001年 / 57卷 / 47期

基金：

新加坡国家研究基金会;

关键词：

isochromanols; cyclization; mercury and compounds; oxygen;

D O I：

10.1016/S0040-4020(01)00963-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of isochromanes containing hydroxy substituents at the 4- and 3-positions has been achieved. The key step for the synthesis of the isochroman-4-ols entailed an oxidative mercury mediated ring closure of 2-(prop-1-enyl)phenylmethanol derivatives, while in the synthesis of the isochroman-3-ols the key step involved ozonolysis of 2-(prop-2-enyl)phenylmethanol derivatives. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：9623 / 9634

页数：12

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