Return to dialysis after renal transplantation.: Which would be the best way?

被引:50
作者
Arias, M [1 ]
Escallada, R [1 ]
De Francisco, ALM [1 ]
Rodrigo, E [1 ]
Fernández-Fresnedo, G [1 ]
Setién, MA [1 ]
Piñera, C [1 ]
Ruiz, JC [1 ]
Herráez, I [1 ]
Cotorruelo, J [1 ]
机构
[1] Univ Cantabria, Dept Nephrol, Margues de Vadecilla Hosp, E-39005 Santander, Spain
关键词
kidney transplantation; chronic allograft nephropathy; complications; anemia; morbi mortality;
D O I
10.1046/j.1523-1755.61.s80.15.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Return to dialysis after renal transplantation. Which would be the best way? The exact moment to return to dialysis when a graft fails has not clearly been established. Furthermore, there is no agreement with respect to whether the guidelines accepted for patients entering dialysis for the first time are adequate for this subgroup of patients with advanced renal failure, due to the special characteristics of these patients, derived from the immunosuppressive medications they are taking among other accompanying factors. We reviewed a group of renal transplant patients who returned to dialysis and compared them with a group of patients entering dialysis for the first time. Patients with chronic renal failure due to graft failure had a poorer renal function at the time entering dialysis and a more profound anemia. Additionally, complications considered such as the number of hispital admissions during the first year after initiation of dialysis were considereably higher in the group of transplanted patients. We advocate for an earlier referral to the dialysis unit, a more aggressive erythropoietin therapy in the phase of advanced renal failure due to chronic alloggraft nephropathy, and in selected cases retransplantation before definitive graft loss.
引用
收藏
页码:S85 / S88
页数:4
相关论文
共 9 条
[1]   Double versus single renal allografts from aged donors [J].
Andrés, A ;
Morales, JM ;
Herrero, JC ;
Praga, M ;
Morales, E ;
Hernández, E ;
Ortuño, T ;
Rodício, JL ;
Martínez, MA ;
Usera, G ;
Díaz, R ;
Polo, G ;
Aguirre, F ;
Leiva, O .
TRANSPLANTATION, 2000, 69 (10) :2060-2066
[2]  
[Anonymous], 1997, Am J Kidney Dis, V30, pS67
[3]  
HAKIM RM, 1995, J AM SOC NEPHROL, V6, P1319
[4]   Improved graft survival after renal transplantation in the United States, 1988 to 1996. [J].
Hariharan, S ;
Johnson, CP ;
Bresnahan, BA ;
Taranto, SE ;
McIntosh, MJ ;
Stablein, D .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (09) :605-612
[5]   Timely initiation of dialysis: A urea kinetic approach [J].
Keshaviah, PR ;
Emerson, PF ;
Nolph, KD .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1999, 33 (02) :344-348
[6]   Level of renal function at the initiation of dialysis in the US end-stage renal disease population [J].
Obrador, GT ;
Arora, P ;
Kausz, AT ;
Ruthazer, R ;
Pereira, BJG ;
Levey, AS .
KIDNEY INTERNATIONAL, 1999, 56 (06) :2227-2235
[7]   UREA KINETICS AND WHEN TO COMMENCE DIALYSIS [J].
TATTERSALL, J ;
GREENWOOD, R ;
FARRINGTON, K .
AMERICAN JOURNAL OF NEPHROLOGY, 1995, 15 (04) :283-289
[8]  
2000, NEPHROL DIAL TRAN S4, V15, P43
[9]  
2000, NEPHROL DIAL TRAN S4, V15, P33