Efficacy of vitamin-C (L-ascorbic acid) in reducing genotoxicity in fish (Oreochromis mossambicus) induced by ethyl methane sulphonate

被引：28

作者：

Guha, B ^{[1
]}

Khuda-Bukhsh, AR ^{[1
]}

机构：

[1] Univ Kalyani, Dept Zool, Kalyani 741235, W Bengal, India

来源：

CHEMOSPHERE | 2002年 / 47卷 / 01期

关键词：

genotoxicity; antimutagen; tilapia; chromosome aberrations; micronuclei; sperm head anomaly;

D O I：

10.1016/S0045-6535(01)00308-3

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The genotoxic effects of ethyl methane sulphonate (EMS) have been assessed in a fish, Oreochromis mossambicus with endpoints including chromosome aberrations, abnormal red blood cell nuclei., abnormal sperm morphology, and protein content (both qualitative and quantitative) of selected tissues, namely, muscle, heart, eye, brain, gill, liver, spleen and kidney. EMS caused chromosomal aberrations, nuclear anomalies in red blood cells, abnormal sperm morphology, and alteration of protein synthesis in various tissues. Some of the EMS toxicity appeared to be modulated and ameliorated in this fish by vitamin-C treatment. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：49 / 56

页数：8

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