Cowpea mosaic virus as a scaffold for 3-D patterning of gold nanoparticles

被引：168

作者：

Blum, AS

Soto, CM

Wilson, CD

Cole, JD

Kim, M

Gnade, B

Chatterji, A

Ochoa, WF

Lin, TW

Johnson, JE

Ratna, BR

机构：

[1] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA

[2] Univ Texas, Dept Elect Engn, Richardson, TX 75083 USA

[3] Scripps Res Inst, Dept Biol Mol, La Jolla, CA 92037 USA

来源：

NANO LETTERS | 2004年 / 4卷 / 05期

关键词：

D O I：

10.1021/nl0497474

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Different mutants of Cowpea Mosaic Virus (CPMV) have been used as scaffolds to bind 2 and 5 nm gold nanoparticles through gold-sulfur bond formation at specific locations on the virus to produce patterns of specific interparticle distances. TEM images confirm that the bound gold particles produce patterns of gold nanoparticles that correlate well with models built from the known locations of the inserted cysteine groups on the capsid. These results demonstrate that it is possible to use CPMV mutants as nanoscale scaffolds to place gold nanoparticles at fixed interparticle distances.

引用

页码：867 / 870

页数：4

共 19 条

[1] Self-assembly of a two-dimensional superlattice of molecularly linked metal clusters [J].