A study of anti-carbonic anhydrase II antibodies in rheumatic autoimmune diseases

被引：22

作者：

Ono, M ^{[1
]}

Watanabe, K ^{[1
]}

Miyashita, Y ^{[1
]}

Inagaki, Y ^{[1
]}

Ueki, H ^{[1
]}

机构：

[1] Kawasaki Med Sch, Dept Dermatol, Kurashiki, Okayama 7010192, Japan

来源：

JOURNAL OF DERMATOLOGICAL SCIENCE | 1999年 / 21卷 / 03期

关键词：

carbonic anhydrase II; autoantibody; rheumatic autoimmune disease;

D O I：

10.1016/S0923-1811(99)00032-8

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Autoantibodies to human carbonic anhydrase II (CAII) were screened by ELISA in 109 sera from Asian-Japanese patients with systemic lupus erythematosus (SLE), primary Sjogren's syndrome (Sjs), progressive systemic sclerosis (PSS) and dermatomyositis (DM). Anti-CAII antibodies were positive in 24.1% of SLE, 20.0% of primary Sjs, 16.7% of PSS and 25.0% of DM. On the other hand, sera from atopic dermatitis, bullous pemphigoid and psoriasis patients showed no activity for anti-CAII antibodies. CAII could be a common exonuclear autoantigen in subsets of rheumatic autoimmune diseases. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：183 / 186

页数：4

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