Metagenomic Diagnosis of Bacterial Infections

被引：71

作者：

Nakamura, Shota

Maeda, Norihiro ^{[2
]}

Miron, Ionut Mihai

Yoh, Myonsun

Izutsu, Kaori

Kataoka, Chidoh

Honda, Takeshi

Yasunaga, Teruo

Nakaya, Takaaki

Kawai, Jun ^{[2
]}

Hayashizaki, Yoshihide ^{[2
]}

Horii, Toshihiro

Iida, Tetsuya ^{[1
]}

机构：

[1] Osaka Univ, Int Res Ctr Infect Dis, Microbial Dis Res Inst, Suita, Osaka 5650871, Japan

[2] Yokohama Inst, RIKEN, Yokohama, Kanagawa, Japan

来源：

EMERGING INFECTIOUS DISEASES | 2008年 / 14卷 / 11期

关键词：

D O I：

10.3201/eid1411.080589

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient's feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with this metagenomic approach.

引用

页码：1784 / 1786

页数：3

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