Moving or Stopping Mitochondria: Miro as a Traffic Cop by Sensing Calcium

被引：49

作者：

Cai, Qian ^{[1
]}

Sheng, Zu-Hang ^{[1
]}

机构：

[1] NINDS, Synapt Funct Sect, NIH, Bethesda, MD 20892 USA

来源：

NEURON | 2009年 / 61卷 / 04期

关键词：

KINESIN HEAVY-CHAIN; AXONAL-TRANSPORT; MOTILITY; SYNAPSES; MILTON; DYNEIN;

D O I：

10.1016/j.neuron.2009.02.003

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Mitochondrial transport in neurons and their spatial distribution among synapses are directly correlated with synaptic activity. One paper in this issue of Neuron (MacAskill et al.) and two papers recently published in Cell (Wang and Schwarz) and PNAS (Saotome et al.) provide compelling evidence that Miro serves as a calcium sensor that controls mitochondrial mobility.

引用

收藏

页码：493 / 496

页数：4

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