Intracellular distribution of rubella virus nonstructural protein P150

被引：54

作者：

Kujala, P ^{[1
]}

Ahola, T ^{[1
]}

Ehsani, N ^{[1
]}

Avuinen, P ^{[1
]}

Vihinen, H ^{[1
]}

Kääriäinen, L ^{[1
]}

机构：

[1] Univ Helsinki, Inst Biotechnol, Electronmicroscopy Unit, FIN-00014 Helsinki, Finland

来源：

JOURNAL OF VIROLOGY | 1999年 / 73卷 / 09期

关键词：

D O I：

10.1128/JVI.73.9.7805-7811.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antiserum prepared against an amino-terminal fragment of rubella virus (RUB) nonstructural polyprotein was used to study RUB-infected Vero cells. Replicase protein P150 was associated with vesicles and vacuoles of endolysosomal origin and later with large, convoluted, tubular membrane structures. Newly incorporated bromouridine was associated with the same structures and specifically with small membrane invaginations, spherules, indicating that these structures may he the sites of viral RNA synthesis.

引用

页码：7805 / 7811

页数：7

共 31 条

[1] REPLICATION OF SEMLIKI FOREST VIRUS - AN ELECTRON MICROSCOPIC STUDY [J].