Making carbon-nitrogen bonds in biological and chemical synthesis

被引：715

作者：

Hili, Ryan ^{[1
]}

Yudin, Andrei K. ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Res Labs, Toronto, ON M5S 3H6, Canada

来源：

NATURE CHEMICAL BIOLOGY | 2006年 / 2卷 / 06期

关键词：

D O I：

10.1038/nchembio0606-284

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The function of many biologically active molecules requires the presence of carbon-nitrogen bonds in strategic positions. The biosynthetic pathways leading to such bonds can be bypassed through chemical synthesis to synthesize natural products more efficiently and also to generate the molecular diversity unavailable in nature. © 2006 Nature Publishing Group.

引用

页码：284 / 287

页数：4

共 20 条

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