Outcome of pregnancy in type 1 diabetes mellitus (T1DMP): results from combined diabetes-obstetrical clinics in Dublin in three university teaching hospitals (1995-2006)

被引：17

作者：

Al-Agha, R. ^{[1
]}

Firth, R. G. ^{[1
]}

Byrne, M. ^{[1
]}

Murray, S. ^{[1
]}

Daly, S. ^{[2
]}

Foley, M. ^{[3
]}

Smith, S. C. ^{[4
]}

Kinsley, B. T. ^{[1
]}

机构：

[1] Mater Misericordiae Univ Hosp, Dublin Diabet Pregnancy Ctr, Dublin 7, Ireland

[2] Coombe Womens Hosp, Dublin, Ireland

[3] Natl Matern Hosp, Dublin 2, Ireland

[4] Rotunda Hosp, Dublin, Ireland

来源：

IRISH JOURNAL OF MEDICAL SCIENCE | 2012年 / 181卷 / 01期

关键词：

T1DM; Pregnancy; Outcomes; Macrosomia; Perinatal mortality; Combined diabetes/obstetrical clinic; GLYCEMIC CONTROL; SPONTANEOUS-ABORTION; WOMEN; NATIONWIDE; NETHERLANDS; MACROSOMIA; AUDIT;

D O I：

10.1007/s11845-011-0781-6

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Objective To compare the pregnancy outcomes in all T1DMP attending at combined (diabetes-obstetric) outpatients clinics in three university teaching hospitals in Dublin from 1995 to 2006 with a non-diabetic control population (C) attending at antenatal outpatient clinics at the same hospitals over the same period. Methods T1DMP (n = 600) were compared with control non-diabetic pregnancies (n = 142,498). Results The spontaneous abortion rate was 15% in T1DMP versus 8% in C (p < 0.0001). Perinatal mortality rate was 3.3% in T1DMP compared to 0.9% in C (p < 0.001). The incidence of foetal macrosomia was 29% in T1DMP versus 16% in C (p < 0.001). Conclusions Pregnancy outcomes in T1DMP remain worse than in the general population despite management of T1DMP in combined obstetric/diabetes clinics in a single centre using similar management protocols. These outcomes in our study population of T1DMP in Dublin appear better than some previously reported studies.

引用

页码：105 / 109

页数：5

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