Hematopoietic stem cell transplantation using umbilical cord blood progenitors:: review of current clinical results

被引：67

作者：

Benito, AI

Diaz, MA

González-Vicent, M

Sevilla, J

Madero, L

机构：

[1] Univ Autonoma Madrid, Nino Jesus Childrens Hosp, Dept Hematol Oncol, Madrid 28009, Spain

[2] Univ Autonoma Madrid, Nino Jesus Childrens Hosp, Bone Marrow Transplantat Unit, Madrid, Spain

来源：

BONE MARROW TRANSPLANTATION | 2004年 / 33卷 / 07期

关键词：

umbilical cord blood; UCB; children; transplantation; hematopoieteic transplant;

D O I：

10.1038/sj.bmt.1704405

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Umbilical cord blood ( CB) has been rapidly established as an alternative source of stem cells to bone marrow for allogeneic- related and unrelated hematopoietic transplantation. To date, almost 70 000 CB units are available for transplantation and more than 2000 CB transplants ( CBT) have been performed, mostly in children, for the treatment of a variety of malignant and nonmalignant conditions. Consider able experience has been rapidly accumulated in this field and many aspects of CBT have been elucidated, while other questions remain unresolved. A concise review of the clinical results achieved after related and unrelated CBT is presented and discussed.

引用

收藏

页码：675 / 690

页数：16

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