Closer look at structure of fully hydrated fluid phase DPPC bilayers

被引:155
作者
Kucerka, Norbert [1 ]
Tristram-Nagle, Stephanie [1 ]
Nagle, John F. [1 ]
机构
[1] Carnegie Mellon Univ, Dept Phys, Pittsburgh, PA 15213 USA
关键词
D O I
10.1529/biophysj.106.086017
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
X-ray data are presented for the benchmark dipalmitoylphosphatidylcholine lipid bilayer in the most biologically relevant state in which the bilayers are fully hydrated and in the fluid (liquid-crystalline) phase. Form factors F(q(z)) are obtained from a combination of two sample preparations, oriented stacks of bilayers for qz extending to 0.85 angstrom(-1) and unilamellar vesicles for smaller qz. Modeling obtains the electron density pro. le and values for the area per molecule, for the locations of the component groups, and for the different types of thicknesses of the bilayer, such as the hydrocarbon thickness and the steric thickness.
引用
收藏
页码:L83 / L85
页数:3
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