Essential role of hypertrophic chondrocytes in endochondral bone development

被引：31

作者：

Chung, UI ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Div Tissue Engn, Bunkyo Ku, Tokyo 1138655, Japan

来源：

ENDOCRINE JOURNAL | 2004年 / 51卷 / 01期

关键词：

endochondral bone formation; hypertrophic chondrocyte; osteogenesis; vascular invasion; Indian hedgehog;

D O I：

10.1507/endocrj.51.19

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：19 / 24

页数：6

共 39 条

[1] The transcrintion factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6 [J].

Akiyama, H ;

Chaboissier, MC ;

Martin, JF ;

Schedl, A ;

de Crombrugghe, B .

GENES & DEVELOPMENT, 2002, 16 (21) :2813-2828

[2] Activated β-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2 mediated signal transduction [J].

Bain, G ;

Müller, T ;

Wang, X ;

Papkoff, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 301 (01) :84-91

[3] Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization [J].

Bi, WM ;

Huang, WD ;

Whitworth, DJ ;

Deng, JM ;

Zhang, ZP ;

Behringer, RR ;

de Crombrugghe, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (12) :6698-6703

[4] Sox9 is required for cartilage formation [J].

Bi, WM ;

Deng, JM ;

Zhang, ZP ;

Behringer, RR ;

de Crombrugghe, B .

NATURE GENETICS, 1999, 22 (01) :85-89

[5] High bone density due to a mutation in LDL-receptor-related protein 5 [J].

Boyden, LM ;

Mao, JH ;

Belsky, J ;

Mitzner, L ;

Farhi, A ;

Mitnick, MA ;

Wu, DQ ;

Insogna, K ;

Lifton, RP .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (20) :1513-1521

[6] The parathyroid hormone parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation [J].

Chung, UI ;

Lanske, B ;

Lee, KC ;

Li, E ;

Kronenberg, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (22) :13030-13035

[7] Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development [J].

Chung, UI ;

Schipani, E ;

McMahon, AP ;

Kronenberg, HM .

JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (03) :295-304

[8] Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3 [J].

Colvin, JS ;

Bohne, BA ;

Harding, GW ;

McEwen, DG ;

Ornitz, DM .

NATURE GENETICS, 1996, 12 (04) :390-397

[9] Fibroblast growth factor receptor 3 is a negative regulator of bone growth [J].

Deng, CX ;

WynshawBoris, A ;

Zhou, F ;

Kuo, A ;

Leder, P .

CELL, 1996, 84 (06) :911-921

[10] VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation [J].

Gerber, HP ;

Vu, TH ;

Ryan, AM ;

Kowalski, J ;

Werb, Z ;

Ferrara, N .

NATURE MEDICINE, 1999, 5 (06) :623-628

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